Put simply, popular fascinations with the end of the world did not begin with COVID-19, nor, in our view, will they end with it. Taken literally, rather than as a bad pun, this observation about the longue durée of apocalypticism provokes new and important questions which I seek to answer. How do human imaginations of the biomedical and spiritual future alter life in the present? What happens, in this forward-looking temporality, to human reflections on the past to ‘lessons learned’ about old diseases now eradicated, or past sins now atoned for?

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